Isometric Hand-Grip Exercise for Preventing Thrombosis and Occlusion of Midline Venous Catheters: A Randomized Controlled Trial

Starting soon · Not applicable

Conditions studied: Midline Catheter

In brief

evaluate whether hand-grip ball exercises reduce thrombosis and occlusions of Midline catheters in hospitalized patients.

Key facts

Study ID

NCT07654101

Run by

University Hospital Padova

People needed

840

Starts

2026-07-06

Expected to finish

2027-09-01

Last updated by the study team

2026-06-17

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Midline catheter insertion for planned intravenous therapy lasting ≥ 7 days. Age between 18 and 70 years. Catheter inserted in the upper limb (forearm). Ability to understand and perform hand exercises with the limb bearing the venous catheter.
• Written informed consent.

You may not qualify if…

• Pre-existing superficial or deep venous thrombosis of the limb used for the Midline catheter.
• Limb injuries or amputations. Motor or neurological impairment of the hand. Life expectancy < 7 days. Cognitive impairment/delirium. Medical contraindications to active upper-limb movement.

Full record on ClinicalTrials.gov

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