Music Therapy for Oral Mucositis Pain in Pediatric Patients

Starting soon · Not applicable

Conditions studied: Oral Mucosa Discomfort, Pediatric Cancer, Mucositis Oral

In brief

This mixed-methods pilot study will examine the effect of music therapy on oral mucositis pain in pediatric oncology patients. Oral mucositis, characterized by painful ulcerative lesions in the mouth, is a common side effect of high-dose chemotherapy and hematopoietic stem cell or bone marrow transplantation. Despite its high prevalence and impact on quality of life, effective pain management strategies for pediatric oral mucositis remain limited and often rely heavily on medications that may cause significant side effects or provide insufficient relief. Music therapy may offer a promising non-pharmacologic adjunct for reducing pain, yet no studies to date have specifically evaluated its use for oral mucositis pain in pediatric patients.

Key facts

Study ID

NCT07653360

Run by

University of California, San Francisco

People needed

50

Starts

2026-07-01

Expected to finish

2027-05-31

Last updated by the study team

2026-06-17

Who can join

Age: 6 and older, up to 64. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Phase 1
• Child ages 6-18 years old
• Child has received music therapy and experienced oral mucositis
• Parent/guardian 18 years and older
• Able to communicate in English

You may not qualify if…

• Phase 1
• Diagnosis of a developmental disorder that would prevent engagement in the active music-making or passive music-listening intervention or completion of study measures.
• Significant pre-existing hearing loss or impairment that would interfere with participation in the interventions.

Where it is running

• University of California, San Francisco — San Francisco, California, United States

Full record on ClinicalTrials.gov

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