Efficacy of Mixed Reality Motor-Cognitive Exercise Interventions
Completed · Not applicable
Conditions studied: Intervention 1: Cognitive and Physical Training, Intervention 2: Multimodal Exercise
In brief
This study aimed to compare the effects of an 8-week mixed reality motor-cognitive training (MR-MCT) intervention to an active comparison group on cognitive and physical functioning and age-related biomarkers in older adults aged 60 years or older with cognitive frailty.
Key facts
- Study ID
- NCT07652996
- Run by
- University of Michigan
- People needed
- 30
- Starts
- 2026-02-03
- Expected to finish
- 2026-05-08
- Last updated by the study team
- 2026-06-17
Who can join
Age: 60 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- age 60 years or older;
- self-determined to be able to exercise safely;
- voluntarily completing all study activities;
- voluntarily signing the informed consent;
- willing to be randomized to either MR-MCT intervention group or the active comparison group; and
- meeting one of the following criteria:
- having subjective cognitive decline (self-report) or MCI: indicated by a Mini-Cog TM score of <4 to increase sensitivity of MCI;
- exhibiting pre-physical frailty or physical frailty, as indicated by a score of 1-2 (pre-frailty) or 3-5 (frailty) on the 5-item FRAIL scale.
- low physical activity, defined as less than 600 Metabolic Equivalent of Task (MET)-min/week and fewer than two 10-min sessions of strengthening exercises per week in the past three months on the International Physical Activity Questionnaire -Short Form (IPAQ-SF) with Muscle Strength.
You may not qualify if…
- recent history of myocardial infarction, stroke, or physical limitations as identified on the Physical Activity Readiness Questionnaire (PARQ);
- Severe obesity: Body mass index (BMI) of 40 or higher; or
- concurrent participation in another intervention study.
Where it is running
- School of Kinesiology, University of Michigan — Ann Arbor, Michigan, United States
Full record on ClinicalTrials.gov
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