Perioperative Myocardial Injury in Patients Undergoing Coronary Artery Bypass Grafting: A Prospective Clinical Study

Starting soon

Conditions studied: Myocardial Injury, Coronary Artery Disease

In brief

Perioperative myocardial injury (PMI) following coronary artery bypass grafting (CABG) is associated with postoperative morbidity, mortality, and long-term outcomes. High-sensitivity troponin assays and cardiac MRI offer reliable diagnostic tools for PMI, but evidence regarding optimal diagnostic thresholds and perioperative imaging strategy is limited. This prospective clinical study aims to determine the incidence of perioperative myocardial injury using multimodal assessments including high-sensitivity troponin, electrocardiogram, echocardiography, cardiac MRI, and perioperative cardiovascular events.

Key facts

Study ID

NCT07650487

Run by

Second Hospital of Jilin University

People needed

150

Starts

2026-07-01

Expected to finish

2027-07-30

Last updated by the study team

2026-06-16

Who can join

Age: 21 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 21 years
• Undergoing CABG for unstable angina
• Able to provide written informed consent
• No major cardiovascular event in the prior 6 months

You may not qualify if…

• Significant hepatic, renal, or other major organ dysfunction
• Pregnancy or breastfeeding
• Withdrawal during the study
• Contraindication to cardiac MRI (metal implants, claustrophobia, etc.)

Where it is running

• the Second Hospital of Jilin University — Changchun, Jilin, China

Full record on ClinicalTrials.gov

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