Feasibility and Acceptability of Amani

Starting soon · Phase 1/Phase 2

Conditions studied: Sickle Cell Disease

In brief

Adults with sickle cell disease (SCD) experience severe pain, emotional distress, and social isolation that diminish their quality of life. This project will test Amani, a novel virtual reality supportive care intervention designed to improve coping skills and strengthen peer support. If feasible and acceptable, Amani offers an accessible digital supportive care intervention to improve psychological well-being and quality of life among individuals living with SCD.

Key facts

Study ID

NCT07648043

Run by

Massachusetts General Hospital

People needed

40

Starts

2026-11-01

Expected to finish

2028-06-30

Last updated by the study team

2026-08-07

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults (≥ 18 years) who are diagnosed with sickle cell disease
• Primarily followed at the Massachusetts General Hospital (MGH) Sickle Cell Disease Center
• Have ability to comprehend and speak English given Amani is currently only available in English.

You may not qualify if…

• Have severe psychiatric (psychotic disorder, bipolar disorder) or cognitive impairment which the treating hematologist believes would preclude ability to participate in the clinical trial

Where it is running

• Massachusetts General Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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