The Impact of Ventilator Synchrony on Muscle Relaxant Consumption and Surgeon Satisfaction During Laparoscopic Cholecystectomy.

Starting soon · Not applicable

Conditions studied: Muscle Relaxant Consumption, Mechanical Ventilation, Laparoscopic Cholecystectomy

In brief

The goal of this clinical trial is to investigate the Impact of adding SIMV Synchronization to our standard PCV-VG mode of ventilation on muscle relaxant consumption, the frequency of relaxant top-ups and surgeon satisfaction during Laparoscopic Cholecystectomy surgeries in ASA I\&II. The main question it aims to answer is do Ventilator synchrony (PCV-VG+SIMV) reduces muscle relaxant consumption and improves surgeon satisfaction by minimizing the perception of inadequate paralysis? Primary hypothesis: Ventilator synchrony (PCV-VG+SIMV) reduces muscle relaxant consumption and improves surgeon satisfaction by minimizing the perception of inadequate paralysis. Primary outcome; 1. Compare total intraoperative rocuronium consumption (mg/kg) between PCV-VG and PCV-VG + SIMV 2. To determine the frequency of additional muscle relaxant requests

Key facts

Study ID

NCT07647770

Run by

Hitham Mohammed Aly Elsayed

People needed

60

Starts

2026-08-01

Expected to finish

2029-06-01

Last updated by the study team

2026-06-15

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 18-60 years undergoing elective laparoscopic cholecystectomy.
• ASA (American Society of Anesthesiologists) physical status I-II
• BMI 18-35 kg/m²

You may not qualify if…

• Severe COPD or restrictive lung disease
• Neuromuscular disorders
• Emergency surgery
• Morbid obesity

Where it is running

• King Fahd University Hospital — Khobar, Eastern Province, Saudi Arabia

Full record on ClinicalTrials.gov

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