The Effect of Mental Fatigue on Upper Extremity Functional Performance

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Conditions studied: Mental Fatigue

In brief

Mental fatigue (MF) is known to impair cognitive performance and may negatively affect physical performance. While its effects on lower-extremity functional performance have been investigated, little is known about the influence of MF on upper-extremity physical performance tests commonly used in sports and rehabilitation settings. This randomized crossover study will investigate the effects of experimentally induced mental fatigue on upper-extremity physical performance in 16 healthy physically active adults. Participants will complete both a mental fatigue condition, involving a prolonged Stroop task, and a control condition consisting of watching an emotionally neutral documentary. Before and after each condition, participants will perform the Upper Quarter Y Balance Test, Reactive Upper Quarter Y Balance Test, Closed Kinetic Chain Upper Extremity Stability Test, and Seated Single-Arm Shot Put Test. Subjective mental fatigue, cognitive performance, motivation, and perceived exertion will also be assessed. The findings will improve understanding of whether mental fatigue influences upper-extremity physical performance test outcomes and may assist clinicians and researchers in interpreting these assessments in sports medicine and rehabilitation contexts.

Key facts

Study ID

NCT07645404

Run by

Izmir Bakircay University

People needed

16

Starts

2026-07-01

Expected to finish

2026-12-01

Last updated by the study team

2026-06-15

Who can join

Age: 18 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age between 18 and 35 years
• Healthy (no neurological, cardiovascular or musculoskeletal disorders of any kind)
• Male or female
• No prior knowledge of the concept of mental fatigue
• Not currently taking medications that affect cognition or neuromuscular performance
• According to the International Physical Activity Questionnaire, being physically active at a minimum level of 1500 MET-min/week

You may not qualify if…

• Previous major upper limb injury (last 6 months)
• Involvement in another concurrent physical or cognitive intervention study
• Use of caffeine and heavy efforts 24 hours prior each trial
• Suffering from colour vision deficiencies
• Not eating a standardized meal, the morning of each trial and the evening before each trial

Where it is running

• Vrije Universiteit Brussel — Brussels, Pleinlaan 2, Belgium

Full record on ClinicalTrials.gov

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