Mechanical Power and Pulmonary Complications in CABG Surgery

Starting soon

Conditions studied: Postoperative Pulmonary Complications, Coronary Artery Bypass Graft Surgery (CABG), Prolonged Mechanical Ventilation

In brief

This prospective observational study evaluates the association between intraoperative mechanical power (MP) - a composite measure of the total energy delivered to the lungs during mechanical ventilation - and postoperative pulmonary complications (PPCs) and prolonged mechanical ventilation in adult patients undergoing elective coronary artery bypass graft (CABG) surgery with cardiopulmonary bypass (CPB). Intraoperative ventilatory parameters including tidal volume, respiratory rate, airway pressures, and PEEP will be recorded and used to calculate MP and driving pressure (DP). No additional interventions will be applied beyond standard clinical care.

Key facts

Study ID

NCT07639489

Run by

Fusun Gozen

People needed

110

Starts

2026-06-01

Expected to finish

2026-09-01

Last updated by the study team

2026-06-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 years or older
• Scheduled for elective, first-time isolated CABG surgery
• Use of cardiopulmonary bypass (CPB)
• Intraoperative mechanical ventilation applied under general anesthesia with recordable ventilator data
• Provision of written informed consent

You may not qualify if…

• Emergency cardiac surgery
• Off-pump CABG (without CPB)
• Preoperative requirement for invasive mechanical ventilation
• Advanced chronic lung disease
• Incomplete or unreliable intraoperative ventilatory data
• Intraoperative use of advanced non-standard support (ECMO)

Where it is running

• Bursa Yüksek İhtisas Training and Research Hospital, Bursa, Türkiye — Bursa, Turkey (Türkiye)

Full record on ClinicalTrials.gov

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