Comparison of Acupressure, Ibuprofen, and Chewing Gum for the Management of Post-Archwire Orthodontic Pain

Starting soon · Not applicable

Conditions studied: Malocclusion

In brief

The goal of this clinical trial is to find out which method works best to reduce pain after braces are adjusted for the first time (when the first archwire is placed). The study will compare three approaches: acupressure (applying pressure on a specific point on the hand), ibuprofen (a pain-relief medicine), and chewing sugar-free gum. It will also check how safe these methods are and whether patients need extra pain medicine. The main questions the researchers want to answer are: Which method reduces orthodontic pain the most after the first archwire is placed? Do patients need extra painkillers in any of the groups? Are there any problems with braces (such as loose brackets or wire issues) within the first week? Researchers will compare the three groups to see which option gives the best pain relief during the first few days after braces are activated. Participants will: Be placed into one of three groups: acupressure, ibuprofen, or chewing gum Use their assigned method after their first orthodontic wire is placed Rate their pain at different time points using a simple pain scale (VAS) Report if they take any extra pain medicine Be checked for any brace-related problems for up to 7 days This study may help improve comfort and pain management for patients starting orthodontic treatment.

Key facts

Study ID

NCT07638644

Run by

Bahria University

People needed

105

Starts

2026-07-01

Expected to finish

2027-07-01

Last updated by the study team

2026-06-11

Who can join

Age: 15 and older, up to 35. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age 15 to 35 years
• Complete permanent dentition
• Undergoing comprehensive fixed orthodontic treatment
• Scheduled for initial archwire placement
• Ability to comply with study procedures
• Written informed consent provided (or parental/guardian consent for participants younger than 18 years)

You may not qualify if…

• Pregnant or lactating
• Systemic disorders that may affect pain perception
• Periodontal disease
• Neurological abnormalities that may affect pain perception
• Known sensitivity to chewing gum
• Documented allergy to ibuprofen
• Use of adjunctive orthodontic appliances
• Use of analgesics, anti-inflammatory medications, or other medications that may affect pain perception within 24 hours before enrollment

Full record on ClinicalTrials.gov

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