The Effect of Respiratory Muscle Training on Cognitive Performance

Recruiting now · Not applicable · Has a placebo group

Conditions studied: Respiratory Muscle Training

In brief

Determine if exercise training for the respiratory muscles improves cognitive performance during periods when breathing against a resistance.

Key facts

Study ID

NCT07637331

Run by

Indiana University

People needed

32

Starts

2026-03-27

Expected to finish

2027-04-01

Last updated by the study team

2026-06-26

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 18-40 years old
• Body mass index <30 kg/m2
• Naïve to IMT
• >75% of predicted forced expiratory volume in 1 second (FEV1) / forced vital capacity (FVC) (FEV1/FVC)
• Access to smart phone or tablet with internet

You may not qualify if…

• Diagnosed:
• Cardiovascular disease
• Respiratory disease (including asthma)
• Metabolic disease
• Currently pregnant
• Unable to adhere to the IMT protocol
• Answering 'yes' to any of the questions on page one of the PAR-Q+
• Abnormal cognition assessed via the Montreal Cognitive Assessment (score of 25 or less)
• Self-reported color blindness
• Significant acute or chronic medical, neurologic, or illness in the participant that, in the judgment of the Principal Investigator, could compromise subject safety, limit the ability of the participant to complete the study, and/or compromise the objectives of the study

Where it is running

• Indiana University — Bloomington, Indiana, United States (enrolling)

Full record on ClinicalTrials.gov

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