Sensing in Sleep Deep Brain Stimulation

Recruiting now · Not applicable

Conditions studied: Parkinson's Disease and Parkinsonism, Dyssomnia

In brief

Participants in this study have Parkinson's Disease and already have a device, called the Percept RC Deep Brain Stimulation device implanted. People with Parkinson's disease often have issues related to sleep such as bad quality of sleep, waking up often and sleep apnea (breathing stops and starts during sleep). For this study, participants will be sleeping overnight in the study sleep lab for two nights. One night, Deep Brain Stimulation (DBS) device turned on and one night with the DBS off, either in this order or the reverse.

Key facts

Study ID

NCT07636720

Run by

The University of Texas Health Science Center at San Antonio

People needed

20

Starts

2026-02-27

Expected to finish

2028-02-01

Last updated by the study team

2026-06-09

Who can join

Age: 40 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ability of subject to understand and the willingness to sign a written informed consent document.
• Males and females; Age 40-80
• Subjects with the diagnosis of idiopathic PD consistent with the United Kingdom Parkinson Disease society brain bank criteria, or documented diagnosis of Parkinson Disease who have a Deep Brain Implant, Percept RC device to subthalamic nucleus (STN) or Globus pallidus internus (GPi).
• Willingness to adhere to the PSG regimen and turn DBS off for one night.
• A score of ≥23 on the Montreal Cognitive Assessment (MoCA)
• Be willing to stop any sleep hypnotics such as benzodiazepines and Ambien, with a 3 day washout period.

You may not qualify if…

• History of severe cardiovascular disease, untreated obstructive sleep apnea (OSA).
• History of other neurological disorders affecting the central nervous system such as stroke, multiple sclerosis, tumors, amyotrophic lateral sclerosis or muscle disease such as muscular dystrophy, myopathy.
• History of Dementia.
• Report dopaminergic medication changes in the past month.

Where it is running

• The University of Texas Health Science Center at San Antonio - Brain Health Center — San Antonio, Texas, United States (enrolling)

Full record on ClinicalTrials.gov

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