Clinical Evaluation of an AI Risk Prediction System (AI-TRiPS)

Starting soon · Early Phase 1

Conditions studied: Trauma, Injury, Decision Support Systems, Clinical

In brief

The goal of this clinical study is to evaluate a software device and its impact on clinician behaviour during the initial management of trauma patients in a real-world clinical setting. Known as the AI-TRiPS Device this software uses real-time prehospital data and machine learning-based risk predictions which are displayed digitally for hospital trauma teams prior patient arrival. The investigators will use a Stepped Wedge Cluster Randomised Controlled study design with an integrated process evaluation. The Device will be deployed across the London Major Trauma System where the Major Trauma Centres will be the clusters. Each cluster will transition from control (standard care) to intervention at a pre-specified time (time of transition is randomised). Primary Outcome: Clinician behaviour, assessed via the accuracy of risk prediction and clinician confidence. Secondary Outcome: Clinician acceptability, care process metrics, patient outcomes, and safety endpoints. Primary study population: Hospital trauma clinicians, following initial resuscitation of each eligible trauma patient, who will complete electronic questionnaires. Secondary study population: Adult trauma patients, data will be collected for the duration of their index admission to hospital, to assess outcomes and enable comparison with clinician risk predictions.

Key facts

Study ID

NCT07634185

Run by

Queen Mary University of London

People needed

1200

Starts

2026-06-01

Expected to finish

2027-12-01

Last updated by the study team

2026-06-08

Who can join

Age: 16 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Clinician Participants
• Senior clinical decision-maker involved in the initial trauma resuscitation (e.g. consultant or senior trainee in emergency medicine, anaesthesia, intensive care medicine, or surgery).
• Based at one of the four participating Major Trauma Centres.
• Able and willing to provide informed consent.
• Completed the required study-specific training.
• Trauma Patients
• Aged 16 years and above.
• Treated and transported to a participating Major Trauma Centre by London's Air Ambulance.
• Managed by one or more participating trauma clinicians during the resuscitation.

You may not qualify if…

• Clinician Participants
• ● Decline or withdraw informed consent at any stage.
• Trauma Patients
• Aged under 16
• Not treated by London's Air Ambulance.
• Transported to a non-participating hospital.
• Not managed by any participating clinicians.
• Presenting with injuries resulting from burns, hangings, drownings, or isolated psychiatric emergencies.
• Have registered a national NHS data opt-out or otherwise requested that their routine clinical data not be used for research.

Full record on ClinicalTrials.gov

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