End-Tidal CO2 (ETCO2) Trends in Out-of-Hospital Cardiac Arrest

Running, not enrolling

Conditions studied: Prehospital Resuscitation, End-Tidal Carbon Dioxide, Cardiac Arrest, Out-Of-Hospital, Prehospital Emergency Medical Services

In brief

The investigators aim to assess the relationship between patient characteristics, prehospital treatments, and vital signs to determine if a threshold EtCO2 value, a change in EtCO2 value (final - initial), or a trend in EtCO2 (positive/negative) is a better predictor of patient survival to discharge. The secondary aim of this project is to identify significant predictors of neurologically intact patient survival as indicated by a cerebral performance category (CPC) score of 1-2.

Key facts

Study ID

NCT07632430

Run by

Office of the Medical Director for EMS in Oklahoma City and Tulsa

People needed

3500

Starts

2024-01-01

Expected to finish

2026-09-30

Last updated by the study team

2026-06-09

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• EHR's resulting from 9-1-1 response
• Adult patients (aged 18+ at time of cardiac event)
• experiencing out-of-hospital cardiac arrest (OHCA)
• transported by an agency under OMD oversight
• must have at least 2 EtCO2 values captured during care Exclusion Criteria
• EHR's resulting from inter-facility scheduled or unscheduled medical transfers
• pediatric patients (those aged <18 at time of incident) or unknown age
• ROSC obtained prior to arrival of EMS
• insufficient vital sign data

Where it is running

• Office of the Medical Director of EMS for Metropolitan Oklahoma City and Tulsa — Oklahoma City, Oklahoma, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.