Post-Operative Spinal Block Duration and Pain Relief After Hip Replacement Surgery: Comparing Single-Shot Spinal Ropivacaine and Bupivacaine

Starting soon · Phase 4

Conditions studied: Hip Osteoarthritis, Hip Arthroplasty Replacement, Postoperative Pain After Ambulatory Surgery

In brief

This study aims to determine whether isobaric ropivacaine is more suitable than isobaric bupivacaine for spinal anesthesia in outpatient total hip arthroplasty (THA). The study will evaluate whether ropivacaine allows faster recovery of sensory and motor function while still providing adequate surgical anesthesia and postoperative pain control. Additional aims are to assess the effects of the anesthetic technique on same-day discharge rates, postoperative recovery, urinary retention, opioid consumption, and patient satisfaction after outpatient THA.

Key facts

Study ID

NCT07631091

Run by

University of Turku

People needed

176

Starts

2026-06-01

Expected to finish

2028-05-01

Last updated by the study team

2026-06-05

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• 18 - 80 years of age
• Scheduled for a primary elective total hip arthroplasty
• Patient must be a candidate for same day discharge
• Informed consent understood and signed
• Patient is 160 - 186 cm tall

You may not qualify if…

• Scheduled bilateral THA
• Contraindication to or failed spinal anesthesia
• Allergy or contraindication to NSAIDs (e.g. chronic kidney disease)
• Diabetes requiring insulin medication
• Preoperative chronic use of illegal substances
• Renal insufficiency (eGFR < 60)
• Unstable psychiatric conditions
• Severe neurological disorder
• Cognitive deficiencies preventing informed consent
• Language barrier preventing completion of study
• Pregnancy or breastfeeding
• Chronic pain syndrome

Full record on ClinicalTrials.gov

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