Post-op Prednisone and Glucose Monitoring in TKA

Starting soon · Phase 4

Conditions studied: Osteoarthritis, Unicompartmental Knee Arthroplasty, Total Hip Arthroplasty (THA)

In brief

This study compares the efficacy of a 5-day post-operative oral prednisone regimen (40 mg daily) with the standard intraoperative steroid regimen, focusing on pain, swelling, range of motion, opioid use, and glucose levels monitored continuously.

Key facts

Study ID

NCT07630896

Run by

Columbia University

People needed

104

Starts

2026-07-01

Expected to finish

2028-03-01

Last updated by the study team

2026-06-05

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Undergoing Primary Unicompartmental Knee Arthroplasty or Total Hip Arthroplasty
• Age 18 and above

You may not qualify if…

• Steroid therapy
• Narcotic use within past 3 months
• History of corticosteroid intolerance
• Pregnancy
• Uncontrolled diabetes
• Doesn't own smart phone
• Drop Criteria:
• 2nd dose of IV dexamethasone

Where it is running

• Columbia University Irving Medical Center — New York, New York, United States

Full record on ClinicalTrials.gov

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