A Pilot Study: Micro and NanoPlastics in Association With Crohn's Disease

Starting soon

Conditions studied: Crohn's Disease (CD)

In brief

Micro and nanoplastics (MNPs) are environmental contaminants found in food and water. Recent evidence suggests these particles may be linked to intestinal inflammation and changes in gut bacteria, which are key features of Crohn's Disease (CD). This study aims to investigate if patients with Crohn's Disease have a reduced ability to clear these plastic particles and how this affects their immune system and intestinal health.

Key facts

Study ID

NCT07630883

Run by

Mak Wing Yan

People needed

90

Starts

2026-06-15

Expected to finish

2031-12-31

Last updated by the study team

2026-06-05

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Cases:
• Age 18-80 years
• Confirmed diagnosis of Crohn's disease (for cases)
• Ability to provide informed consent.
• Control:
• Age 18-80 years old
• No history of major large bowel resection
• Ability to provide informed consent.

You may not qualify if…

• Cases:
• Antibiotic/probiotic use within 4 weeks
• History of gastrointestinal malignancy
• Presence of stoma
• Currently Pregnant
• Advanced terminal medical illness, e.g. terminal malignancies; end staged renal failure and liver failure
• Control:
• Currently Pregnant
• Advanced terminal medical illness, e.g. terminal malignancies; end staged renal failure and liver failure
• Inability in giving consent

Where it is running

• Prince of Wales Hospital — Hong Kong, Hong Kong

Full record on ClinicalTrials.gov

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