Gastric Feeding for the Prevention of Stroke-Associated Pneumonia

Starting soon · Phase 4

Conditions studied: Stroke

In brief

This randomized controlled trial aims to compare the effectiveness of early post-pyloric feeding versus gastric feeding in preventing SAP in patients with severe ischemic stroke. The main question to answer is whether post-pyloric feeding group is better than the gastric feeding group for preventing SAP.

Key facts

Study ID

NCT07630090

Run by

Jinling Hospital, China

People needed

174

Starts

2026-06-15

Expected to finish

2027-09-15

Last updated by the study team

2026-06-05

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥ 18 years
• Diagnosis of severe ischemic stroke, with NIHSS score > 16 [15-16]
• Confirmed dysphagia via swallowing assessment (Kubota Water Swallowing Test ≥ grade 3, or confirmed aspiration risk by FEES/VFSS)
• Time from onset to enrollment ≤ 72 hours
• Expected survival ≥ 7 days
• Non-mechanically ventilated patients
• Signed informed consent from patient or legal representative.

You may not qualify if…

• Diagnosed with pneumonia upon admission
• High risk of gastrointestinal bleeding or perforation
• Intestinal obstruction or gastrointestinal obstruction
• Severe liver or kidney dysfunction
• Advanced malignant tumor
• Pregnancy or breastfeeding
• Refusal to participate in the study

Where it is running

• Jinling Hospital, Medical School of Nanjing University, Nanjing — Nanjing, Jiangsu, China

Full record on ClinicalTrials.gov

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