COPD Flare-Up Clinic After Severe Exacerbations

Starting soon · Not applicable

Conditions studied: COPD, COPD Exacerbation (AECOPD)

In brief

This prospective randomized controlled trial evaluates whether a specialized "COPD flare-up clinic service" improves outcomes in patients following an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Patients presenting to the emergency department with AECOPD and discharged or hospitalized will be randomized 1:1 to either structured follow-up in a dedicated flare-up clinic or standard follow-up by scheduled telephone interviews. The researches hypothesize that structured follow-up in a specialized clinic will reduce recurrent exacerbations, optimize long-term COPD management, and improve patients' quality of life compared to standard care.

Key facts

Study ID: NCT07629869
Run by: Tel-Aviv Sourasky Medical Center
People needed: 240
Starts: 2026-07-01
Expected to finish: 2028-12-31
Last updated by the study team: 2026-06-23

Who can join

Age: 40 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Prior COPD diagnosis based on clinical and spirometry accepted criteria.
Acute exacerbation of COPD as the main reason for ED arrival.
Ability to perform in-person and telephone follow-up.
Agree to participate, with a signed informed consent.

You may not qualify if…

Symptomatic heart failure as the main reason for emergency department visit in the last 6 months.
Uncontrolled comorbidity.
Vulnerable Populations: To ensure ethical compliance and participant safety, the study will exclude vulnerable populations. This includes pregnant women, and any person lacking the mental or legal capacity to provide independent informed consent.

Where it is running

Tel Aviv Sourasky Medical Center, Tel Aviv, 6423906 — Tel Aviv, Israel

Full record on ClinicalTrials.gov

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