Non-invasive Auricular Vagus Nerve Stimulation (taVNS) on Postural Control and Autonomic Responses in Stroke

Recruiting now · Not applicable

Conditions studied: Stroke

In brief

This randomized controlled trial is conducted to determine the effects of transcutaneous auricular Vagus nerve stimulation (taVNS) on postural control in stroke patients (e.g., improvements in balance, mobility, and functional stability) and to evaluate the effects of taVNS on autonomic nervous system responses in stroke patients (e.g., changes in heart rate variability, blood pressure variability, skin conductance, and temperature).

Key facts

Study ID

NCT07629687

Run by

Riphah International University

People needed

22

Starts

2026-05-20

Expected to finish

2026-11-20

Last updated by the study team

2026-07-20

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Age between 18 to 70years who are diagnosed with ischemic brain injury, intracerebral hemorrhage shown by magnetic resonance imaging, or computed tomography.
• First occurrence of stroke characterized by a unilateral lesion, with an onset time (acute/ subacute) < 6 months
• With balance impairment (BBS Score = 21-44);
• no or mild spasticity on the lower-limb assessed by Modified Ashworth Scale (MAS ≤ 2);
• sufficient cognition to follow the instructions provided by the therapists and the computer.

You may not qualify if…

• Individuals exhibiting unstable vital signs, consciousness disorders, or an inability to cooperate with examination and treatment procedures
• Those with a heart rate below 60 beats per minute, or with implantable devices such as pacemakers or cochlear implants.
• Other medical or psychological conditions affecting participation

Where it is running

• Railway General Hospital, Rawalpindi — Islamabad, Punjab Province, Pakistan (enrolling)

Full record on ClinicalTrials.gov

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