Feasibility of Structured Resistance Training After Lower Extremity Fracture

Starting soon · Not applicable

Conditions studied: Lower Extremity Fractures

In brief

Adults recovering from surgically managed diaphyseal femur or tibia fractures often experience persistent weakness, pain, and functional limitations despite successful fracture healing. This prospective, non-randomized pilot study evaluates the feasibility and acceptability of a structured, supervised resistance training program initiated approximately 12 weeks after surgery, compared with usual postoperative care alone. The study will assess recruitment, adherence, retention, and protocol fidelity, and will collect exploratory patient-reported and physical function outcomes to inform the design of a future randomized controlled trial.

Key facts

Study ID

NCT07629180

Run by

London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

People needed

40

Starts

2026-06-15

Expected to finish

2031-06-15

Last updated by the study team

2026-06-05

Who can join

Age: 20 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 20 to 65 years
• Diaphyseal femur or tibia fracture treated surgically with locked intramedullary nail fixation
• Cleared for full weight bearing with adequate fracture healing and no major complications
• Able to provide written informed consent in English without an interpreter
• Able to understand instructions and safely participate in supervised exercise

You may not qualify if…

• Bilateral fractures or open fractures; Polytrauma
• Cognitive impairment affecting participation or ability to provide informed consent
• Severe cardiac, respiratory, or neurological conditions that preclude exercise participation
• Chronic pain syndromes or recent opioid dependence
• Pre-existing severe lower limb disability
• Requires an interpreter for consent or cannot follow exercise instructions independently
• Unable to provide consent due to language barrier

Where it is running

• London Health Sciences Centre — London, Ontario, Canada

Full record on ClinicalTrials.gov

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