How Fig Polyphenols Affect Blood Sugar and Insulin Levels After Eating in Adults at Risk for Diabetes

Running, not enrolling · Not applicable

Conditions studied: Pre Diabetic

In brief

The study purpose is to understand how the body absorbs and metabolizes nutrient-like components in dried figs called polyphenols over 24 hours. The study is also done to know if polyphenols will help a hormone called insulin work better in the body, so to look further into the possibility of figs being a functional food for the pre-diabetic population.

Key facts

Study ID

NCT07625046

Run by

Clinical Nutrition Research Center, Illinois Institute of Technology

People needed

5

Starts

2026-03-12

Expected to finish

2027-05-15

Last updated by the study team

2026-06-04

Who can join

Age: 30 and older, up to 50. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Be between 30-50 years old.
• Have a BMI of 25-35 kg/m².
• Have fasting blood glucose between 100-125 mg/dL or Glycated hemoglobin (HbA1c) between 5.7-6.4%.
• Be non-smokers for at least 12 months.
• Be generally healthy, with no major organ-related diseases.
• Not take medications or supplements that could interfere with the study.
• Be able to follow study procedures, including dietary restrictions and scheduled visits

You may not qualify if…

• Smoker
• Vegetarian
• Taking over the counter supplements (e.g. fiber supplements, probiotics and/or prebiotics, antioxidants, anti-inflammation) and/or taking prescription medications that may interfere with study procedures or endpoints (e.g. Gastrointestinal medications, antibiotics) within the last 30 days
• Have cancer other than non-melanoma skin cancer in previous 5 years
• Taking unstable dose of hormonal contraceptive and/or stable dose less than 6 months
• Planning to become pregnant
• Pregnant and/or breast-feeding
• Excessive exercisers or trained athletes
• Excessive coffee/tea drinker
• Donated blood within last 3 months
• Have allergies/intolerances to foods consumed in the study
• Regular consumption of dried fruits exceeds > 2 servings per day
• Actively losing weight/ trying to lose weight (unstable body weight fluctuations of > 5 lbs in 3 months)
• Addicted to drugs or alcohol or have significant psychiatric or neurological disturbances
• Past smokers may be allowed in the study if stopped >2 years

Where it is running

• Illinois Tech — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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