An Online Intervention to Reduce E-cigarette Use and Cigarette Smoking Risk in Adolescents

Starting soon · Not applicable

Conditions studied: E-cigarette Use, Cigarette Smoking Risk

In brief

The goal of this clinical trial is to learn if a brief digital intervention can reduce e-cigarette use and prevent cigarette smoking initiation in teenagers ages 12-17. The main questions it aims to answer are: * Compared to the control condition, does the intervention reduce e-cigarette use frequency in teenagers? * Compared to the control condition, does the intervention reduce risk to start smoking cigarettes in teenagers? Researchers will compare the digital intervention to see if it leads to greater reductions in e-cigarette use and smoking risk than a waitlist control condition. Participants will complete 5 brief online surveys across 12 weeks, and some will be selected to do a post-intervention virtual interview. In this interview, participants will be asked to share their opinions about the intervention and identify areas that need refinement.

Key facts

Study ID

NCT07624292

Run by

University of Southern California

People needed

150

Starts

2026-07-01

Expected to finish

2027-03-30

Last updated by the study team

2026-06-03

Who can join

Age: 12 and older, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• be between the ages of 12 to 17
• be able to read English
• be a current resident of California
• report vaping at least one day per week in the past month
• report no history of cigarette use at screening and baseline
• have access to a computer or mobile device with internet access

You may not qualify if…

• currently receiving nicotine cessation services

Full record on ClinicalTrials.gov

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