Dusting vs Fragmentation Laser Cystolithotripsy for Pediatric Bladder Stones

Recruiting now · Not applicable

Conditions studied: Bladder Calculi, Pediatric Bladder Stones, Pediatric Urolithiasis

In brief

Bladder stones are a clinically relevant pediatric urological condition that may require endoscopic treatment. Transurethral Holmium:YAG laser cystolithotripsy is a minimally invasive option for selected children with bladder stones. This prospective randomized trial will compare two Holmium:YAG laser strategies during transurethral cystolithotripsy in children with a single bladder stone less than 3 cm: dusting and fragmentation. Children will be randomized to undergo laser dusting or laser fragmentation during transurethral cystolithotripsy. The primary outcome is total operative time. Secondary outcomes include laser time, need for active fragment extraction, endoscopic stone-free status at the end of the procedure, ultrasound-assessed stone-free status during follow-up, intraoperative complications, postoperative urinary symptoms, urinary tract infection, need for postoperative catheterization, and hospital stay.

Key facts

Study ID

NCT07623980

Run by

Beni-Suef University

People needed

110

Starts

2026-05-06

Expected to finish

2027-05-01

Last updated by the study team

2026-06-03

Who can join

Age: any, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Children aged less than 18 years.
• Radiologically confirmed single bladder stone less than 3 cm.
• Suitable for transurethral cystolithotripsy.
• Fit for general anesthesia.
• Written informed consent from parents or legal guardians.

You may not qualify if…

• Giant bladder stones more than 3 cm.
• Urethral pathology preventing safe transurethral access.
• Major lower urinary tract anomaly or neurogenic bladder.
• Active untreated urinary tract infection.
• Coagulation disorder or contraindication to endoscopic surgery.

Where it is running

• Department of Urology- Beni-Suef University Hospitals — Banī Suwayf, Beni Suweif Governorate, Egypt (enrolling)

Full record on ClinicalTrials.gov

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