Wearable Accelerometers for Predicting Perioperative Risk in Elderly Patients

Recruiting now

Conditions studied: Post Induction Hypotension

In brief

This single-center prospective cohort study is designed to evaluate whether preoperative physical activity measured by a wearable accelerometer is associated with cardiovascular autonomic function and whether it can help predict post-induction hypotension in elderly patients undergoing elective non-cardiac surgery. Patients aged 65 years or older scheduled for general anesthesia with tracheal intubation will undergo preoperative physical activity monitoring using an ActiGraph wearable accelerometer. Activity-related parameters, including sedentary time, light-, moderate-, and vigorous-intensity activity, daily step count, and sleep duration, will be recorded. Cardiovascular autonomic function will be assessed perioperatively using noninvasive continuous hemodynamic monitoring, with baroreflex sensitivity-related indices derived from continuous blood pressure and beat-to-beat timing data. The primary outcome is post-induction hypotension. Secondary outcomes include early intraoperative hypotension, postoperative complications, and 30-day mortality. This study aims to clarify the relationship between habitual physical activity and autonomic regulation in older surgical patients and to provide evidence supporting future prehabilitation strategies.

Key facts

Study ID

NCT07621120

Run by

Peking Union Medical College Hospital

People needed

100

Starts

2026-06-15

Expected to finish

2027-12-31

Last updated by the study team

2026-06-02

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age ≥65 years
• Scheduled for elective non-cardiac surgery
• American Society of Anesthesiologists (ASA) physical status I-III
• Planned to undergo general anesthesia
• Planned tracheal intubation
• The patient and family members are able to understand the study protocol, are willing to participate, and provide written informed consent

You may not qualify if…

• Severe vascular disease
• Secondary hypertension
• Limb tremor disorders, such as Parkinson disease
• Inability to wear a wrist-based wearable accelerometer for any reason
• Inability to measure upper-extremity blood pressure
• Atrial fibrillation or other arrhythmias unsuitable for baroreflex sensitivity measurement
• Mental or psychiatric conditions resulting in inability to cooperate with study procedures

Where it is running

• Peking Union Medical College Hospital — Beijing, Beijing Municipality, China (enrolling)

Full record on ClinicalTrials.gov

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