TransREctus Sheath PrePeritoneal Procedure (TREPP) for Inguinal Hernia Repair
Recruiting now · Not applicable
Conditions studied: Inguinal Hernia, Inguinal Hernia Repair
In brief
Inguinal hernia repair remains one of the most commonly performed surgical procedures worldwide. Tension-free repair with mesh augmentation is the predominant treatment option, either achieved by preperitoneal laparoscopic hernioplasty or Lichtenstein procedure (LP). As the recurrence rate is reduced to less than 5 % after mesh repair, nowadays, long-term morbidity associated with open inguinal hernia repair is mainly related to chronic postoperative inguinal pain (CPIP). Despite many hypotheses about the possible causes for CPIP, there is now consensus that involvement of inguinal nerves plays a major role. The trans rectus sheath extra-peritoneal procedure (TREPP) is a minimally invasive open approach utilizing the rectus sheath to access the preperitoneal space. It has shown promise in providing effective repair with potential advantages in cosmesis, postoperative pain, and recurrence rates. It is a medial approach avoiding the interference with the course of all (three) inguinal nerves through lateral abdominal wall.
Key facts
- Study ID
- NCT07618884
- Run by
- Assiut University
- People needed
- 30
- Starts
- 2025-04-15
- Expected to finish
- 2026-09-01
- Last updated by the study team
- 2026-06-01
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults with primary unilateral or bilateral inguinal hernia
You may not qualify if…
- Strangulated hernias.
- Severe comorbidities precluding surgery ((ASA Class IV,V)
Where it is running
- Faculty of Medicine-Assiut University -Assiut-Egypt — Asyut, Asyut Governorate, Egypt (enrolling)
Full record on ClinicalTrials.gov
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