Bone Metabolism in Patients Treated With 3d Printed Aligners Versus Thermoformed Aligners
Starting soon · Not applicable
Conditions studied: Bone Metabolism, Orthodontic Aligners
In brief
Background: Orthodontic forces induce tissue reactions by triggering perturbations from orthodontic appliances, which lead to the modelling and remodelling of alveolar bone. Despite the growing popularity of 3D-printed aligners, no studies have compared their effects on bone metabolism in comparison with thermoformed aligners. Aim: This study aims to assess bone metabolism in patients undergoing treatment with 3D-printed aligners versus thermoformed aligners.
Key facts
- Study ID
- NCT07617571
- Run by
- Alexandria University
- People needed
- 30
- Starts
- 2026-06-01
- Expected to finish
- 2026-07-01
- Last updated by the study team
- 2026-06-01
Who can join
Age: 18 and older, up to 25. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Minor malocclusion (2 to 4 mm of crowding) .
- Patients in need for Antero-posterior expansion and labial tipping of incisors without interproximal reduction
- No use of anti-inflammatory drugs or antibiotics in the past 6 months.
- Periodontal parameters of gingival index <1 and no pocketing with a generalized pocketing depth of <3mm.
- Radiographic parameters of no crestal bone loss.
- No history of smoking.
You may not qualify if…
- Signs of inflammation of the gingiva, and periodontitis.
- Systemic conditions (kidney disease, HIV, and liver disease).
- Teeth missing or poor oral hygiene.
- Bone disease e.g.; osteoporosis.
Where it is running
- Faculty of Dentistry, Alexandria University — Alexandria, Egypt
Full record on ClinicalTrials.gov
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