Fixed-Mass Different Volumes Bupivacaine TAP Block After Cesarean
Starting soon · Phase 4
Conditions studied: TAP Block, Caesarean Section, Postoperative Pain
In brief
Cesarean section is commonly associated with moderate to severe postoperative pain, which may delay mobilisation, impair breastfeeding, and affect mother-infant bonding. Although opioids, NSAIDs, and neuraxial techniques are commonly used for post-cesarean analgesia, their side effects have encouraged the use of peripheral nerve blocks such as the transversus abdominis plane block. The TAP block is a fascial plane block that provides analgesia by depositing local anaesthetic between the internal oblique and transversus abdominis muscles. Its efficacy after cesarean section has been demonstrated, particularly when long-acting intrathecal opioids are not used. However, the optimal local anaesthetic volume and dose remain unclear. Since the TAP block depends on adequate spread of local anaesthetic, larger volumes may improve analgesic coverage, but increasing the dose may raise the risk of systemic toxicity. Therefore, this study investigates whether using the same fixed mass of bupivacaine in two different volumes affects the analgesic efficacy of TAP block after cesarean section, hypothesising that the larger volume may provide better postoperative analgesia.
Key facts
- Study ID
- NCT07616180
- Run by
- Cairo University
- People needed
- 50
- Starts
- 2026-06-06
- Expected to finish
- 2026-10-01
- Last updated by the study team
- 2026-06-01
Who can join
Age: 18 and older. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- full-term parturients,
- aged > 18 years
- ASA physical status II
- patients who are scheduled for elective CS with Pfannenstiel incisions under spinal anaesthesia.
You may not qualify if…
- Parturients with contraindications to spinal anaesthesia,
- Having a scar or infection at the site of the block
- BMI > 35 Kg/m2,
- on chronic use of pain medications,
- Refusing to participate.
Full record on ClinicalTrials.gov
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