Structured Combined Exercise Program in Postmenopausal Women: Effects on Heart Rate Variability and Menopausal Symptoms

Recruiting now · Not applicable

Conditions studied: Postmenopausal, Menopausal Symptoms, Autonomic Nervous System Diseases, Sleep Wake Disorders

In brief

The goal of this clinical trial is to learn whether a structured combined exercise program can improve heart health, menopausal symptoms, sleep quality, and quality of life in postmenopausal women aged 45 to 65 years. The main questions it aims to answer are: Does the exercise program improve heart rate variability, which shows how well the heart is controlled by the nervous system? Does the exercise program lower menopausal symptoms? Does the exercise program improve sleep quality and quality of life? Researchers will compare women who join the exercise program with women who continue their usual daily activities. Participants in the exercise group will take part in a supervised exercise program for 12 weeks. They will exercise 2 days each week. Each session will last 45 minutes and will include warm-up, balance, strengthening, coordination, flexibility, and cool-down exercises. Participants in the control group will continue their usual daily activities during the study.

Key facts

Study ID

NCT07615790

Run by

Fenerbahce University

People needed

40

Starts

2026-04-27

Expected to finish

2026-09-01

Last updated by the study team

2026-05-29

Who can join

Age: 45 and older, up to 65. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Women in the postmenopausal period
• Aged between 45 and 65 years
• Able to communicate and cooperate with the researchers
• Not participating in another structured exercise program
• Willing to participate voluntarily in the study

You may not qualify if…

• Presence of severe cardiovascular, neurological, orthopedic, or psychiatric disease
• Hormone replacement therapy use during the study period
• Cognitive impairment affecting participation
• Uncontrolled hypertension or other unstable medical conditions
• Regular participation in structured exercise training within the last 6 months
• Smoking or alcohol use that may affect heart rate variability measurements

Where it is running

• Fenerbahce University — Istanbul, Atasehir, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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