EOI Block vs. TAP Block in Minimally Invasive Hepatectomy

Starting soon · Not applicable

Conditions studied: Hepatectomy

In brief

This study aims to compare the analgesic efficacy of two different ultrasound-guided nerve blocks-the External Oblique Intercostal (EOI) block and the Subcostal Transversus Abdominis Plane (TAP) block-in patients undergoing minimally invasive hepatectomy. All participants will receive standardized general anesthesia and perioperative care at Seoul National University Hospital. Following anesthesia induction, patients will be randomly assigned to receive either an EOI block or a subcostal TAP block with 0.375% ropivacaine to provide regional pain relief. Postoperative pain will be managed using a combination of scheduled non-opioid analgesics and a fentanyl-based patient-controlled analgesia (PCA) device. The primary objective is to evaluate which regional technique more effectively reduces cumulative opioid consumption during the first 24 hours after surgery. Additionally, the study will assess pain intensity using the Numerical Rating Scale (NRS), the incidence of postoperative nausea and vomiting, and the overall recovery profile, including the time to first ambulation.

Key facts

Study ID

NCT07615231

Run by

Seoul National University Hospital

People needed

140

Starts

2026-06-01

Expected to finish

2027-06-30

Last updated by the study team

2026-06-08

Who can join

Age: 20 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Scheduled to undergo elective robotic or laparoscopic minimally invasive hepatectomy

You may not qualify if…

• American Society of Anesthesiologists physical status IV or higher
• History of chronic pain or current use of analgesics, antidepressants, or anticonvulsants for pain management
• Known hypersensitivity to general anesthetics, opioids, or local anesthetics
• Conversion to open hepatectomy
• Requirement for mechanical ventilation for more than 2 hours within 48 hours postoperatively
• Any other clinical condition that makes the patient unsuitable for participation in the study.

Where it is running

• SNUH — Seoul, South Korea

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.