Multilevel Exercise Response in Rowers

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Conditions studied: Healthy Adult Participants

In brief

This observational study aims to evaluate multilevel physiological, molecular, metabolic, intestinal, immunological, and psychophysiological responses to rowing-specific exercise in elite rowers. The study is designed to investigate how maximal and prolonged rowing ergometer exercise influences integrated adaptive mechanisms related to mitochondrial function, metabolic regulation, intestinal permeability, immune activation, DNA damage response, and psychological status. Thirty members of the Polish Youth National Rowing Team, aged 19-24 years, will participate in the study during two different training periods. During the competitive phase, participants will perform a 2000-m maximal rowing ergometer test, whereas during the preparatory phase they will complete a 6000-m rowing ergometer test. Blood samples and physiological measurements will be collected before exercise, immediately after exercise, and after 1 hour of recovery. The study will assess gene expression, circulating biomarkers, flow cytometry parameters, blood morphology, lactate concentration, continuous glucose monitoring data, wearable metabolic sensor measurements, nutritional status, and psychological responses. The primary objective is to identify integrated biomarkers reflecting exercise load, recovery dynamics, and adaptive capacity in highly trained athletes. The study also aims to improve understanding of the interaction between metabolic, mitochondrial, intestinal, immunological, and psychophysiological responses to intensive exercise in rowing.

Key facts

Study ID

NCT07613619

Run by

Poznan University of Physical Education

People needed

30

Starts

2026-05-17

Expected to finish

2027-01-30

Last updated by the study team

2026-05-29

Who can join

Age: 19 and older, up to 24. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Male and female members of the Polish Youth National Rowing Team.
• Age between 19 and 24 years.
• Regular participation in structured rowing training.
• Medical clearance for participation in maximal exercise testing.
• Ability and willingness to provide written informed consent.

You may not qualify if…

• Lack of consent for blood sampling or study participation.
• Current injury or health condition contraindicating maximal exercise.
• Acute infection, fever, or inflammatory condition at the time of testing.
• Use of anti-inflammatory medications.
• Use of performance-enhancing substances.
• Use of dietary supplements within 3 months before study participation.
• Any medical contraindications identified by the study physician.

Full record on ClinicalTrials.gov

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