Unilateral Ventilation on Cardiopulmonary Bypass During Cardiac Surgery

Starting soon · Not applicable

Conditions studied: Lung Protective Ventilation, Cardiopulmonary Bypass, High-risk Cardiac Patients, Lung Ultrasound, Lung Water Assessment, Pulmonary Complications in Surgical Patients, Single-lung Ventilation, Chest X-ray for Clinical Evaluation, Electrical Impedance Tomography (EIT), Lung Compliance, Oxygenation Indices, Biomarkers of Vascular Endothelial Injury

In brief

This study investigates if single lung ventilation on cardiopulmonary bypass can mitigate postoperative lung water accumulation determined by lung ultrasound in the ventilated lung as compared to the non-ventilated lung in patients at high-risk for developing severe pulmonary complications after cardiac surgery.

Key facts

Study ID

NCT07612709

Run by

Medical University of Vienna

People needed

45

Starts

2026-10-01

Expected to finish

2029-07-31

Last updated by the study team

2026-05-29

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients at increased risk for postoperative pulmonary complications
• Major elective cardiac surgery
• Prolonged duration of cardiopulmonary bypass
• Patients older than 65 years of age
• Informed consent

You may not qualify if…

• Emergency
• Urgent procedures
• Patients with implanted pacemakers
• Patients with internal cardioverter/defibrillators
• Decompensated cardiac disease
• Pulmonary disease
• Recent pneumonia
• Need for temporary perioperative mechanical support
• Patients not willing to participate
• Treatment with inhaled nitric oxide

Where it is running

• General Hospital Vienna — Vienna, State of Vienna, Austria

Full record on ClinicalTrials.gov

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