Retention and Caries Prevention of Giomer Sealant With or Without Diode Laser Pre-treatment: A Randomized Controlled Trial

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Conditions studied: Dental Caries

In brief

This randomized controlled trial evaluates the effect of diode laser pre-treatment on the retention and caries prevention of giomer-based fissure sealants in young adults aged 17-22 years. The study compares sealant application with and without diode laser conditioning on molars with ICDAS 0-2 fissures over a 12-month follow-up period. Primary outcome is sealant retention using Simonsen's criteria, while secondary outcome is caries prevention using modified USPHS criteria. The study hypothesizes that diode laser pre-treatment may improve sealant retention and enhance caries prevention by modifying enamel surface characteristics and improving sealant penetration.

Key facts

Study ID

NCT07612540

Run by

Cairo University

People needed

111

Starts

2026-06-01

Expected to finish

2027-06-01

Last updated by the study team

2026-05-28

Who can join

Age: 17 and older, up to 22. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Young adult Patients Aged 17-22.
• Good oral hygiene (plaque index score 0 or 1).
• Absence of abnormal occlusion habits (e.g. bruxism, nail biting, tooth clenching and mouth breathing).
• Patients approving to participate in the study.

You may not qualify if…

• •Patients with known allergic or adverse reaction to the tested materials.
• Systematic disease that may affect participation.
• Xerostomic patients.

Where it is running

• Faculty of Dentistry Cairo University — Cairo, Egypt
• Faculty of Dentistry — Cairo, Egypt
• Yomna — Cairo, Egypt

Full record on ClinicalTrials.gov

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