HFNC Versus Microstream Advance Nasal Cannula for Oxygenation During ERCP
Recruiting now · Not applicable
Conditions studied: Endoscopic Retrograde Cholangiopancreatography, Hypoxemia
In brief
Endoscopic retrograde cholangiopancreatography (ERCP) procedures are commonly performed under deep sedation and are associated with a risk of hypoxemia, particularly in prone or semi-prone positions. High-flow nasal cannula (HFNC) therapy may improve oxygenation by delivering heated and humidified oxygen at high flow rates, while the Microstream Advance nasal cannula provides simultaneous nasal oxygen delivery and oral oxygen insufflation. This prospective randomized study aims to compare the effectiveness of HFNC and Microstream Advance nasal cannula in maintaining oxygenation during ERCP procedures. Patients undergoing ERCP will be randomized into two groups receiving either HFNC or Microstream Advance nasal cannula oxygen support during sedation. The primary outcomes are the incidence of desaturation and oxygen reserve index (ORi) measurements during the procedure. Secondary outcomes include time to achieve target ORi levels, respiratory complications, and procedure-related adverse events.
Key facts
- Study ID
- NCT07611903
- Run by
- Kocaeli University
- People needed
- 74
- Starts
- 2026-07-14
- Expected to finish
- 2026-12-30
- Last updated by the study team
- 2026-07-15
Who can join
Age: 18 and older, up to 84. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients aged 18 to 84 years
- ASA physical status I-III
- Patients scheduled to undergo ERCP
- Patients who provide written informed consent
You may not qualify if…
- Recent history of upper respiratory tract infection
- History of lung cancer
- Chronic obstructive pulmonary disease
- Asthma
- Body mass index greater than 35 kg/m²
- Refusal to participate in the study
Where it is running
- Kocaeli University Faculty of Medicine Hospital — Kocaeli, Umuttepe, Turkey (Türkiye) (enrolling)
Full record on ClinicalTrials.gov
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