Construction of a Cohort of Elderly Patients With Atrial Fibrillation in Rural China

Recruiting now

Conditions studied: Atrial Fibrillation (AF), Heart Failure, Screening, Progression

In brief

Atrial fibrillation (AF) is a common arrhythmia in aging populations and is strongly associated with an increased risk of heart failure (HF) and adverse cardiovascular outcomes. However, early detection of HF among patients with AF remain inadequate in rural settings. This study aims to screen for HF among older adults with AF in rural China and to conduct long-term follow-up in order to observe the disease progression in patients with AF. This study will recruit at least 2,500 elderly individuals aged between 65 and 80 years, with confirmed diagnoses of AF, residing in rural areas. Participants will undergo HF screening using NT-proBNP testing and echocardiographic assessment. Additionally, data will be collected on electrocardiographic signals, seismocardiography, voice, and demographic characteristics. Following data collection, participants will be followed up every three months to monitor the incidence and progression of HF as well as the occurrence of adverse cardiovascular events.

Key facts

Study ID

NCT07611084

Run by

Jiangsu Taizhou People's Hospital

People needed

2500

Starts

2026-03-14

Expected to finish

2029-12-31

Last updated by the study team

2026-05-28

Who can join

Age: 65 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Permanent residents with local household registration in rural China.
• Aged 65-80 years.
• Electrocardiogram confirmation of AF or possession of a diagnostic certificate for AF issued by a specialist.
• Willing to participate in HF screening.
• Ability to understand the study procedures and provide written informed consent.

You may not qualify if…

• Expected life expectancy of less than 3 months.
• Severe renal insufficiency (Ccr < 30ml/min) or ongoing dialysis treatment.
• Cardiac insufficiency secondary to correctable causes, including hyperthyroid heart disease, anemic heart disease, or uncorrected congenital heart disease.
• Indications for pacemaker implantation without having undergone implantation.
• Chronic obstructive pulmonary disease complicated by type II respiratory failure.
• Special populations, including patients with mental illnesses.

Where it is running

• Department of Cardiology — Taizhou, Jiangsu, China (enrolling)

Full record on ClinicalTrials.gov

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