Clinical Value of Saline Infusion Sonohysterography in the Assessment of Cesarean Scar Defects

Recruiting now

Conditions studied: Infertility

In brief

This study selected patients who underwent cesarean section and were scheduled to undergo Saline Infusion Sonohysterography (SIS) for evaluating the structure of the incision. Clinical characteristics and clinical symptoms were collected. Combined with hysteroscopy, MRI, conventional ultrasound and SIS examination results, the study analyzed the detection rate of cesarean section diverticula by SIS, the changes in diverticulum size and the diagnostic efficacy of residual muscle layer thickness at the incision site. The surgical methods and clinical symptom improvement of patients with CSD after surgery were followed up for half a year to one year. The study aimed to clarify the guiding value of SIS in clinical decision-making and patient prognosis for patients, and to analyze the etiological relationship between the true incidence of CSD and clinical complications. Thus, it provided evidence-based basis for clinical events of cesarean section surgery → CSD → CSD complications → surgical treatment of CSD → patient prognosis, promoting the progress of precise diagnosis and treatment of female reproductive health.

Key facts

Study ID

NCT07610668

Run by

Tang-Du Hospital

People needed

300

Starts

2023-01-01

Expected to finish

2026-07-31

Last updated by the study team

2026-05-28

Who can join

Age: 20 and older, up to 50. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• More than 6 months after cesarean delivery;
• Presenting with clinical symptoms-including abnormal uterine bleeding, dysmenorrhea, prolonged menstrual spotting, or secondary infertility;
• Requiring saline infusion sonohysterography (SIS) to evaluate the cesarean scar.

You may not qualify if…

• Multiple cesarean deliveries;
• Patients contraindicated for saline infusion sonohysterography (SIS), including pregnancy or suspected pregnancy, failure to meet vaginal hygiene criteria, inability to cooperate during the procedure, or suboptimal image quality;
• Cases with incomplete clinical data or lost to follow-up.

Where it is running

• Tang-Du Hospital — Xi'an, Shaanxi, China (enrolling)

Full record on ClinicalTrials.gov

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