R. Officinalis as Pulpotomy Agent in Permanent Teeth With Irreversible Pulpitis

Starting soon · Not applicable

Conditions studied: Irreversible Pulpitis, Pulpotomy, MTA Vital Tooth Pulpotomy

In brief

This study evaluates and compares the clinical and radiographic outcomes of Rosmarinus officinalis and Mineral Trioxide Aggregate (MTA) when used as pulpotomy medicaments in vital mature permanent teeth with irreversible pulpitis. The aim is to determine the effectiveness of both materials in terms of pain reduction and periapical healing. While MTA is considered a gold standard, it has limitations such as high cost, long setting time, and potential discoloration. Therefore, this study investigates Rosmarinus officinalis as a natural, cost-effective alternative with comparable therapeutic potential. This study also provide an alternative to RCT in teeth with irreversible pulpitis

Key facts

Study ID

NCT07610057

Run by

University of Health Sciences Lahore

People needed

100

Starts

2026-06-01

Expected to finish

2026-12-31

Last updated by the study team

2026-05-27

Who can join

Age: 18 and older, up to 40. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Healthy patients (ASA classification 1 and 2) of age range of 18-40 of both sexes would be included.
• Vital mature permanent posterior teeth with deep caries approaching the pulp as seen on periapical x-ray.
• Pain indicative of irreversible pulpitis (spontaneous pain or pain exacerbated by a cold stimulus which could last from a few seconds to hours), which a cold test could reproduce.
• Tooth will be selected on the basis of working diagnosis i.e. successful hemostasis within 5 minutes after removal of coronal pulp.
• Absence of clinical signs or symptoms suggesting a non-vital tooth such as tenderness to percussion or palpation, mobility, presence of abscess, soft tissue swelling or suppurating sinus.
• Absence of radiographic changes as; furcation or periapical pathology, internal or external root resorption or calcification in the canals.
• The tooth structure of selected teeth should be restorable after completion of the treatment

You may not qualify if…

• Patients with ASA classification 3, 4 ,5 and 6 would be
• Patients taking antibiotics within last 2 weeks.
• Teeth with pulp necrosis, cracked tooth, internal or external resorption, calcified canals, acute or chronic apical periodontitis with an associated sinus tract or periapical radiolucency.
• Periodontally compromised tooth.
• Uncooperative patients or failure to obtain authorization from patients.

Where it is running

• Punjab Dental Hospital, Lahore . — Lahore, Punjab Province, Pakistan

Full record on ClinicalTrials.gov

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