A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine
Recruiting now · Phase 4
Conditions studied: Acute Treatment of Migraine
In brief
Acute treatments for migraine may not provide sufficient pain relief after an initial dose, and a second dose of a given medication may be needed to fully abort an attack. International Headache Society (IHS) global practice recommendations for the Acute Treatment of Migraine suggest a second dose of the same medication within the recommended dose limit in people with headache relapse after successful initial treatment of a migraine attack. The primary purpose of this study is to evaluate the safety and tolerability of redosing of rimegepant when taken for the acute treatment of a migraine attack, as it is possible that some patients may benefit from a second dose of rimegepant in this setting.
Key facts
- Study ID
- NCT07609914
- Run by
- Pfizer
- People needed
- 400
- Starts
- 2026-05-28
- Expected to finish
- 2028-05-15
- Last updated by the study team
- 2026-07-29
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Hope Clinical Research — Canoga Park, California, United States (enrolling)
- Neurology Offices of South Florida — Boca Raton, Florida, United States (enrolling)
- Brainstorm Research — Miami, Florida, United States (enrolling)
- Clinical Neuroscience Solutions — Orlando, Florida, United States (enrolling)
- New England Regional Headache Center — Worcester, Massachusetts, United States (enrolling)
- Michigan Headache & Neurological Institute — Ann Arbor, Michigan, United States (enrolling)
- FutureSearch Trials of Dallas — Dallas, Texas, United States (enrolling)
- Headache Wellness Center — Greensboro, North Carolina, United States
- FutureSearch Trials of Neurology — Austin, Texas, United States
- MedStar Health - Department of Neurology — McLean, Virginia, United States
- Proven Endpoints, LLC — Ridgeland, Mississippi, United States
Full record on ClinicalTrials.gov
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