Pneumoperitoneum Pressure and Lung Ultrasound Atelectasis

Recruiting now · Not applicable

Conditions studied: Atelectasis, Perioperative Complication, Pneumoperitoneum

In brief

Elective laparoscopic cholecystectomy may lead to perioperative atelectasis due to pneumoperitoneum-related diaphragmatic elevation and impaired respiratory mechanics. Lung ultrasound (LUS) provides a noninvasive bedside method for evaluating perioperative aeration loss. This prospective randomized controlled study aims to compare the effects of low-pressure (10 mmHg) and standard-pressure (14 mmHg) pneumoperitoneum on perioperative atelectasis assessed by LUS in patients undergoing laparoscopic cholecystectomy under general anesthesia. Changes in LUS scores, respiratory mechanics, oxygenation, and postoperative clinical outcomes will also be evaluated.

Key facts

Study ID

NCT07609615

Run by

Engin Çetin

People needed

112

Starts

2026-06-01

Expected to finish

2026-09-01

Last updated by the study team

2026-06-23

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients aged between 18 and 65 years
• ASA physical status I-II
• Scheduled for elective laparoscopic cholecystectomy under general anesthesia
• Body mass index (BMI) <30 kg/m²
• Ability to provide written informed consent

You may not qualify if…

• Chronic pulmonary disease
• Recent respiratory tract infection
• Thoracic deformity or previous thoracic surgery
• Preoperative pulmonary pathology
• Morbid obesity
• Pregnancy
• Emergency surgery
• Conversion to open surgery
• Requirement for protocol-violating pneumoperitoneum pressure modification
• Refusal to participate in the study

Where it is running

• University of Health Sciences Kocaeli City Hospital — İzmit, Kocaeli, Turkey (Türkiye) (enrolling)

Full record on ClinicalTrials.gov

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