Peripheral pULSe Assessment and Arterial pRessure (PULSAR)

Recruiting now

Conditions studied: Circulatory Shock, Hemodynamic Instability, Hypotension, Shock, Critical Illness

In brief

This prospective multicenter observational study aims to investigate the relationship between palpable peripheral pulses and simultaneously measured arterial blood pressure in adult patients with circulatory shock or impending circulatory failure. Peripheral pulse palpation is routinely used in emergency medicine, trauma care, critical care, and cardiopulmonary resuscitation as a rapid clinical assessment of circulation. However, the association between palpable pulses and actual arterial blood pressure remains poorly validated. Patients treated in emergency departments, intensive care units, operating rooms, and other acute care settings will undergo routine pulse palpation at predefined anatomical locations including carotid, femoral, and radial arteries. Simultaneously measured non-invasive and/or invasive arterial blood pressure values will be recorded from routine clinical monitoring systems. Additional clinical variables relevant to circulatory status will also be collected. The study seeks to define blood pressure thresholds associated with pulse palpability and evaluate the agreement between invasive and non-invasive blood pressure measurements in patients with circulatory shock.

Key facts

Study ID

NCT07609095

Run by

Region Stockholm

People needed

5000

Starts

2026-06-01

Expected to finish

2031-12-31

Last updated by the study team

2026-05-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Clinical signs of circulatory shock or impending circulatory failure
• Availability of non-invasive and/or invasive arterial blood pressure monitoring
• Pulse palpation possible without interfering with emergency care

You may not qualify if…

• Peripheral vascular conditions preventing reliable pulse palpation
• Major extremity amputation affecting assessment sites
• Clinical situations where study procedures interfere with life-saving treatment

Where it is running

• Region Stockholm, all hospitals — Stockholm, Stockholm County, Sweden (enrolling)

Full record on ClinicalTrials.gov

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