Exploring Biomarkers in the Heat and Moisture Exchange Filters

Recruiting now

Conditions studied: Respiratory Inflammation

In brief

When patients undergo major surgery, they are connected to a ventilator during anesthesia. A heat and moisture exchange filter (HME filter) is routinely placed in the ventilator tubing to ensure that the inhaled air is warm and humidified. Today, HME filters are used routinely in all ventilator treatments. They are typically replaced once a day and discarded as regular waste after use. The purpose of this study is to investigate whether HME filters contain proteins and small biological particles from the patient's exhaled air.

Key facts

Study ID

NCT07607977

Run by

Aalborg University Hospital

People needed

10

Starts

2026-05-08

Expected to finish

2027-05-01

Last updated by the study team

2026-05-27

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• ≥18 years, able to understand study information in Danish.
• Admitted for elective surgery for non-malignant conditions with either intravenous or inhalation anaesthesia and invasive mechanical ventilation according to standard practice.
• Expected invasive mechanical ventilation > 1 hour.
• Possess legal capacity.
• Informed, signed consent is obtained.

You may not qualify if…

• Patients who are transferred to the ICU for continuous invasive mechanical ventilation after end of elective surgery.
• Known chronic lung disease.

Where it is running

• Aalborg University Hospital — Gistrup, Denmark (enrolling)

Full record on ClinicalTrials.gov

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