MRI and Local Anesthesia

Starting soon · Not applicable

Conditions studied: Dental Anesthesia

In brief

The purpose of this research is to investigate the utility of using dental-dedicated MRI as a measurement tool to observe and evaluate the administration of local anesthesia in dental patients.

Key facts

Study ID

NCT07602686

Run by

University of Minnesota

People needed

102

Starts

2026-08-20

Expected to finish

2029-07-01

Last updated by the study team

2026-08-06

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult age 18 or older
• Health status of American Society of Anesthesiologists (ASA) class 1 or 2
• Able to provide informed consent
• Able to appear in person at OMRIC on the days indicated for the study

You may not qualify if…

• ASA class 3 or higher
• Pregnant patients
• Taking any medication that would affect pain perception or interact with local anesthetic
• Allergic/history of adverse reaction to local anesthetic or any component in the local anesthetic
• Paresthesia in the area of innervation of Cranial Nerve V3
• Active infection or abscess in the oral and maxillofacial region
• History of temporomandibular disorder, maximum incisal opening less than 15mm
• History of recent dental trauma (within the past 6 months)
• Dental hypersensitivity
• Claustrophobia and/or conditions of anxiety or motion disorder (for MRI purposes)
• Metallic, electronic, or magnetic implants or devices classified as MR Unsafe or Conditional by the American College of Radiology
• Unable to give informed consent

Where it is running

• University of Minnesota — Minneapolis, Minnesota, United States

Full record on ClinicalTrials.gov

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