Patient Positioning for Treatment of Proximal Ureteral Stones

Recruiting now · Not applicable

Conditions studied: Ureteral Stone

In brief

Ureteroscopic management of proximal ureteral stones presents technical challenges including stone retropulsion, prolonged operative time, and conversion to intrarenal treatment. Reverse Trendelenburg positioning has been shown to reduce proximal stone migration and operative time in ureteral stones, while the T-tilt position improves intrarenal stone clearance. The optimal strategy for proximal ureteral stones (treating stones in situ using reverse Trendelenburg versus pushing stones into the kidney followed by intrarenal treatment in T-tilt) remains unknown. This randomized controlled trial compares these two strategies, with primary focus on operative time as a measure of procedural efficiency. A total of 54 patients (27 per arm) will be enrolled at Mount Sinai West.

Key facts

Study ID

NCT07601932

Run by

Icahn School of Medicine at Mount Sinai

People needed

54

Starts

2026-05-21

Expected to finish

2027-12-01

Last updated by the study team

2026-06-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults aged 18 years and older.
• Diagnosed with kidney stones and scheduled for fURS.
• Stone burden > 1 cm and/or multiple stones will be eligible.
• Able and willing to provide informed consent.

You may not qualify if…

• Pregnant persons as determined by pre-operative urine pregnancy test (standard of care at the institution)
• Untreated UTI
• Patients with urinary anomalies (e.g., urinary diversion, ureteral reconstruction, horseshoe kidney)
• Single stone < 1 cm

Where it is running

• Mount Sinai West — New York, New York, United States (enrolling)

Full record on ClinicalTrials.gov

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