Diagnostic Performance and Quantitative Analysis of [18F]FET PET in Brain Tumours

Starting soon

Conditions studied: Brain Tumors

In brief

This is a retrospective study encompassing all \[18F\]FET PET scans performed at our centre. By analysing both static and dynamic scans, conducting in-depth kinetic modelling, and comparing quantitative parameters across different tumour types and clinical contexts, the study aims to determine the true diagnostic value of \[18F\]FET PET in everyday clinical practice. The ultimate goal is to identify imaging biomarkers useful for improving tumour characterisation and distinguishing recurrence from post-treatment changes, thereby strengthening the role of \[18F\]FET PET in modern neuro-oncology.

Key facts

Study ID

NCT07599917

Run by

IRCCS San Raffaele

People needed

69

Starts

2026-06-01

Expected to finish

2026-12-31

Last updated by the study team

2026-05-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients who underwent a brain PET/CT or PET/MRI scan with [18F]FET for clinical reasons during the study period.
• Age ≥ 18 years.
• Indication for the scan related to diagnosis, grading, assessment of treatment response or suspected recurrence of any brain tumour (primary or metastatic).
• Availability of the corresponding static and dynamic images.
• Signed informed consent.

You may not qualify if…

• . Pregnancy or breastfeeding

Full record on ClinicalTrials.gov

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