Speech Amplification Devices for Parkinson Disease: Talker- and Technology-Driven Enhancements

Recruiting now · Not applicable

Conditions studied: Parkinson Disease, Atypical Parkinsonism

In brief

The proposed research aims to investigate the use of speech amplification devices as a potential treatment option for people with Parkinson's disease and related disorders who exhibit hypophonia, a voice disorder that affects over half of those with Parkinson's disease. By characterizing the acoustic and perceptual effects of speech amplification and identifying ways to optimize outcomes through talker- and device-specific enhancements, this project seeks to develop personalized, evidence-based treatment options for hypophonia. The current proposal will move this effort forward by systematically eliciting and modifying speech amplification device output that leverage both behavioral and technological approaches.

Key facts

Study ID

NCT07599696

Run by

Michigan State University

People needed

100

Starts

2024-03-01

Expected to finish

2028-05-31

Last updated by the study team

2026-05-20

Who can join

Age: 50 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Dominant speakers of North American English
• Have received a neurologist's diagnosis of Parkinson disease or parkinsonism (e.g., PSP/MSA/PSP)
• Present with changes in their speech/voice

You may not qualify if…

• History of any other speech, language, or neurological concern other than Parkinson/parkinsonism.
• Uncorrected hearing loss that exceeds a threshold of 40 dB HL in more than one ear (as per baseline screening audiometry) and/or use of a cochlear implant.

Where it is running

• Michigan State University — East Lansing, Michigan, United States (enrolling)

Full record on ClinicalTrials.gov

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