Intra-articular Injection of Medications in TMJ After Arthrocentsis

Starting soon · Not applicable

Conditions studied: Internal Derangement

In brief

The aim of this study: to evaluate the injection of hyaluronic acid and corticosteroids mixture leads to better clinical outcomes in terms of improve maximum mouth opening and reduce pain compared with hyaluronic acid and prp mixture in patients with TMJ internal derangement .

Key facts

Study ID

NCT07598253

Run by

Cairo University

People needed

20

Starts

2026-06-01

Expected to finish

2026-12-30

Last updated by the study team

2026-05-22

Who can join

Age: 18 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients should have one or more signs and symptoms of these
• Symptoms: Patients who report typical symptoms of TMJ dysfunction, such as pain, discomfort, or clicking sounds in the joint, especially when opening or closing the mouth.
• Mouth Opening: Limited range of motion or difficulty with full mouth opening.
• Clicking: Audible clicking.
• Pain: Pain or tenderness around the TMJ, often radiating to the ear, temple, or neck.

You may not qualify if…

• * Previously diagnosed hematological and neurological conditions;
• Previous malignant head and neck neoplasms;
• Uncooperative patients.

Where it is running

• Faculty of dentistry cairo university — Cairo, Cairo Governorate, Egypt

Full record on ClinicalTrials.gov

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