Effects of Remimazolam on Neurocognitive Function in Patients Undergoing Cardiovascular Surgery

Starting soon

Conditions studied: Neurocognitive Disorder, Cardiac Surgery

In brief

The goal of this observational study is to explore the effect of remimazolam-based total intravenous anesthesia on postoperative neurocognitive function in patients who undergo cardiovascular surgery. The main question this study tries to answer is: Does remimazolam influence the incidence of postoperative delirium in cardiovascular surgery? Participants already apply remimazolam-based total intravenous anesthesia as part of their regular medical treatment for general anesthesia to perform cardiac surgery will answer questionnaires about cognitive function after surgery.

Key facts

Study ID

NCT07598019

Run by

Chinese Academy of Medical Sciences, Fuwai Hospital

People needed

210

Starts

2026-06-15

Expected to finish

2027-12-30

Last updated by the study team

2026-05-20

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female adult patients aged 60 years or older
• Receiving elective cardiovascular surgery with cardiopulmonary bypass
• Written Informed consent provided

You may not qualify if…

• Deep hypothermia circulatory arrest
• Breastfeeding or pregnancy
• Mental or legal disability
• Terminal illness with a life expectancy of less than 3 months
• Unable to receive neuro-cognitive evaluation due to language, vision, or hearing impairments

Where it is running

• State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College — Beijing, Beijing Municipality, China

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.