Hematological Indices and Sympathetic Block Response in Neuropathic Pain
Recruiting now
Conditions studied: Neuropathic Pain, Neuropathic Pain Diagnostic Questionnaire (DN4) ≥ 4
In brief
This prospective observational study aims to evaluate the relationship between hematological inflammatory indices and clinical treatment response in patients with neuropathic pain undergoing sympathetic nerve block procedures as part of routine clinical care. Hematological parameters including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR), systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), aggregate index of systemic inflammation (AISI), and red cell distribution width (RDW) will be evaluated before and after treatment. The association between changes in these indices and pain outcomes will be analyzed.
Key facts
- Study ID
- NCT07596823
- Run by
- Ankara City Hospital Bilkent
- People needed
- 120
- Starts
- 2026-06-01
- Expected to finish
- 2027-01-31
- Last updated by the study team
- 2026-06-29
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Age ≥18 years
- Diagnosis of neuropathic pain based on clinical evaluation
- DN4 and/or LANSS scores compatible with neuropathic pain
- Undergoing sympathetic nerve block as part of routine clinical treatment
- Availability of pre-treatment and follow-up hemogram parameters
- Ability to provide written informed consent
You may not qualify if…
- Age <18 years
- Active infection or acute inflammatory disease
- Active malignancy
- History of hematological disease
- Immunosuppressive therapy or systemic corticosteroid use
- Major surgery or severe trauma within the last month
- Pregnancy or breastfeeding
- Autoimmune or rheumatologic inflammatory disease
- Missing follow-up data
Where it is running
- Ankara Bilkent City Hospital — Ankara, Cankaya, Turkey (Türkiye) (enrolling)
Full record on ClinicalTrials.gov
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