Long-Term Engagement and Motivation Through Innovative Strategies in Adapted Physical Activity

Starting soon · Not applicable

Conditions studied: Aging, Healthy, Aging

In brief

Aging is associated with progressive declines in physical, functional, and psychosocial capacities, leading to reduced autonomy, increased risk of falls, chronic diseases, and decreased quality of life. Physical inactivity is a major aggravating factor, despite strong evidence that regular physical activity helps prevent age-related decline. Adapted Physical Activity (APA) has demonstrated beneficial effects on physical function, mental health, pain, and healthcare utilization. However, long-term adherence to APA programs among older adults remains low, with fewer than 20% meeting World Health Organization recommendations. Therefore, innovative strategies are needed to improve sustained engagement in physical activity. This multicenter, randomized, single-blind interventional study aims to compare the effectiveness of different APA strategies on long-term engagement in physical activity among adults aged 60 years and older. A total of 600 participants will be randomized into four groups combining two key factors: (1) autonomy-based vs. non-autonomy-based approaches, and (2) classical APA vs. TEMPA-based APA programs. Each intervention consists of a 12-week program including 24 supervised sessions, with some groups incorporating a progressive transition toward autonomous practice. The primary outcome is long-term physical activity engagement assessed using the QAPPA questionnaire at baseline, 6 months, and 12 months. Secondary outcomes include: Objective and self-reported physical activity levels (questionnaires and wearable devices) Functional capacities (muscle strength, endurance, gait speed, balance, cardiorespiratory fitness) Motivational and perceptual factors (e.g., enjoyment, fatigue, perceived effort, motivation) Quality of life (EQ-5D-5L) Biological markers (inflammatory, metabolic, metabolomic, and epigenetic profiles) to identify predictors of adherence and physiological response Cost-effectiveness and cost-utility analyses (incremental cost-effectiveness ratio) Statistical analyses will be conducted using mixed linear models for repeated measures to evaluate time, group, and interaction effects. Additional analyses will include descriptive statistics, group comparisons, longitudinal trends, and economic evaluations. This study aims to identify effective and sustainable APA strategies to improve long-term physical activity engagement and inform public health policies for older adults.

Key facts

Study ID: NCT07596056
Run by: Centre Hospitalier Universitaire de Nice
People needed: 600
Starts: 2026-09-01
Expected to finish: 2031-09-01
Last updated by the study team: 2026-05-19

Who can join

Age: 60 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

Age 60 or older
Affiliation with, or beneficiary of, a social security system
No objection to the study

You may not qualify if…

Neurocognitive disorder preventing the provision of informed consent (MOCA <18)
Individuals under legal protection
Individuals deprived of liberty
Presence of a physical or cognitive condition preventing participation in the adapted physical activity protocol over 3 months:
Neurocognitive disorder (MOCA <18)
Neurodegenerative disease with severe symptoms preventing participation in the protocol
Neuromuscular disease with severe symptoms preventing participation in the protocol
Severe sensory impairments (blindness or profound deafness)
Amputation of one or more limbs
Non-independent mobility

Where it is running

CHU de Nice - Hopital de Cimiez — Nice, France

Full record on ClinicalTrials.gov

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