The MAI-FOIE Cohort

Starting soon

Conditions studied: Autoimmune Liver Diseases, Immunological Mechanisms

In brief

The MAI-FOIE cohort will be a French multicenter cohort with the development of a biobank including patients with autoimmune, metabolic and medicated liver diseases

Key facts

Study ID: NCT07594990
Run by: Nantes University Hospital
People needed: 800
Starts: 2026-06-01
Expected to finish: 2038-05-30
Last updated by the study team: 2026-06-25

Who can join

Age: 10 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

age≥10 years old
weight≥25kg
AIH (with or without the presence of an overlap) whose diagnosis is validated by at least 2 of the following criteria :
ALT>2N or IgG>1.1N
Presence of autoantibodies : ANA (antinuclear), ML (anti-smooth muscle), SLA (anti-soluble liver antigen), LKM1 (anti-endoplasmic reticulum), LC1 (anti-liver cytosol)
Presence of interface hepatitis on biopsy
signing of a written consent form for participation in the study and for the storage of biological samples research
Control patients :
age≥18 years old
weight≥37kg
Patient with one of the following 3 conditions :
Primary Biliary Cholangitis
Metabolic steatohepatitis
Drug induced hepatitis

You may not qualify if…

Positive HIV serology HBV infection Positive HCV serology and PCR Patients under guardianship or curatorship

Where it is running

CHU d'Angers — Angers, France
CHU de Brest — Brest, France
AP-HP Beaujon — Clichy, France
CHD Vendée — La Roche-sur-Yon, France
CHU de Lille — Lille, France
Hospices Civils de Lyon — Lyon, France
CHU Nantes — Nantes, France
AP-HP Saint-Antoine — Paris, France
CHU Poitiers — Poitiers, France
CHU de Rennes — Rennes, France
CHU de Toulouse — Toulouse, France
CHU de Tours — Tours, France
AP-HP Paul Brousse — Villejuif, France

Full record on ClinicalTrials.gov

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