Investigating the (Cost-)Effectiveness of an Online Social Therapy Platform (ENYOY) for Young People Aged 16-25 on Mental Healthcare Waiting Lists

Starting soon · Not applicable

Conditions studied: Psychological Distress

In brief

This study, run by Amsterdam UMC in the Netherlands, looks at whether an online mental health platform called ENYOY can help improve psychological distress in young people (16-25) who are waiting for mental health care. Young people in the Netherlands aged 16 to 25 can take part if they are experiencing mental health problems, and are currently on a waiting list for mental healthcare. The study lasts 12 months. During this time, participants fill in questionnaires four times (at the start, at 3-months, 6-months, and 12-months). After joining the study, participants are randomly placed into one of two groups: * Intervention group: receives access to the ENYOY platform plus care-as-usual. * Control group: receive care-as-usual. Young people in the intervention group can use the platform for the duration of the study period, with three months of guidence by a coach and/or peer with lived experience with mental health complaints. The platform includes activities based on proven psychological methods. These activities help with things like low mood, anxiety, sleep problems, and confidence. They also get support from a coach and/or a peer (someone who has experienced mental health problems themselves), and access to a safe online community where young people can talk, share experiences, and support each other. The community is moderated to keep it safe and supportive. Taking part may help young people feel psychological stress and improve their mental health. There are no known risks from taking part in this study. Participant recruitment will take place from May 2026 to December 2027. Final follow-up assessments are expected to be completed by December 2028. The study is funded by ZonMw. For questions, you can contact Sascha Struijs (s.y.struijs@vu.nl), or Fenna Hellegers (f.hellegers@amsterdamumc.nl)

Key facts

Study ID

NCT07594756

Run by

Academisch Medisch Centrum - Amsterdam UMC Research BV

People needed

225

Starts

2026-05-18

Expected to finish

2028-12-31

Last updated by the study team

2026-05-19

Who can join

Age: 16 and older, up to 25. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 16-25 years
• On a waiting list for mental healthcare
• Able and willing to consent
• A score of 10 or higher on the CORE-10 questionnaire
• Have personal and private access to a computer, smartphone or tablet.
• Ability and willingness to nominate an emergency contact person, such as a close family member

You may not qualify if…

• Insufficient command of the Dutch language
• Present with acute suicidal behavior or imminent risk of harm to self
• If their psychiatric symptoms are due to an organic cause
• Prior exposure to ENYOY or MOST

Full record on ClinicalTrials.gov

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